Pharmacodynamics of TRPV1 Agonists in a Bioassay Using Human PC-3 Cells
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چکیده
منابع مشابه
Pharmacodynamics of TRPV1 Agonists in a Bioassay Using Human PC-3 Cells
PURPOSE TRPV1 is a multimodal channel mainly expressed in sensory neurons. We aimed to explore the pharmacodynamics of the TRPV1 agonists, capsaicin, natural capsaicinoids, and piperine in an in vitro bioassay using human PC-3 cells and to examine desensitization and the effect of the specific antagonist SB366791. METHODS PC-3 cells expressing TRPV1 were incubated with Fluo-4. Fluorescence em...
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ژورنال
عنوان ژورنال: The Scientific World Journal
سال: 2014
ISSN: 2356-6140,1537-744X
DOI: 10.1155/2014/184526